Wet-lab triage for AI binder-design agents. Submit computational protein designs against a target and receive yeast-display enrichment, NGS counts, and called hits. The Ranomics MCP server gives AI binder-design agents programmatic access to wet-lab validation. Submit a panel of computationally designed proteins or antibody binders against a target, and the upstream Ranomics Platform runs yeast surface display, mammalian display, or deep mutational scanning at library scale. You get back per-sequence enrichment ratios, NGS counts, and called hits. Designed for the AI workflow that has 10,000+ MPNN, RFdiffusion, BindCraft, or BoltzGen candidates and can't afford per-sequence kinetics on all of them. Use Ranomics first to enrich down to the top 100 or 200, then take those to a biophysics vendor for binding kinetics. Seven tools cover the full lifecycle: `list_targets`, `estimate_cost`, `submit_experiment`, `get_experiment_status`, `get_experiment_quote`, `confirm_quote`, `get_experiment_results`. Transport: streamable-http. Auth: Bearer token from https://tools.ranomics.com/account/api-keys. Also published to the official MCP Registry as `com.ranomics/mcp`.

MCP readiness

B · 88/100

Readiness is how fully this listing follows its protocol and how it behaved in our probes over 30 days. It is shown for reference and does not move it in search. Search order and leaderboards use the separate quality grade (here C+, 70.5/100), which weighs availability, conformance, p95 speed and descriptor. How the two differ

Valid MCP handshake	10/10	initialize and tools/list both answered.
Live MCP endpoint	25/25	Endpoint answers the MCP initialize handshake (1970 ms).
Protocol revision	8/10	Speaks MCP 2025-11-25, 1 revision(s) behind 2026-07-28.
Signed descriptor	n/a	No MCP standard defines a signed server descriptor.
Uptime (30 days)	15/15	30/30 probes succeeded over 30 days (100%).
Tool declaration	10/10	Lists 7 tool(s) with descriptions.
Verified identity	5/10	Publisher declared (repository, package or homepage); claim this listing to verify domain control.
Freshness + modern flags	4/5	seen in a source within 7 days.
Auth declaration	2/5	Declares credential scheme: smithery_api_key.

Applicable criteria total 90 points, scaled to 100.

Responsiveness: Responsive (1970 ms; bands ≤2.5 s, ≤5 s, ≤8 s, slower; penalty only).

Measured 2026-11-11.

Nine criteria, the same as the A2A readiness score, read from our daily MCP probe (initialize + tools/list) and 30-day probe history. No MCP standard defines a signed server descriptor, so that criterion is n/a and the other 90 points are scaled to 100. Grades: A>=90, B>=75, C>=60, D>=40, F<40. Display only: search order uses the quality grade.

Compared with peers

Against 53,039 reachable MCP servers in our daily snapshot (2026-11-12 06:46 UTC). Display only; it does not change search order.

Readiness: Higher than 95% of peers; This listing 88 · peer median 81
Latency: Faster than 35% of peers; This listing 460 ms · peer median 326 ms

Where it loses the most points, and how to win them back

Verified identity −5 — Claim the listing and prove control of its domain.
Now: Publisher declared (repository, package or homepage); claim this listing to verify domain control.
Auth declaration −3 — State how to authenticate (an auth scheme, or that none is needed).
Now: Declares credential scheme: smithery_api_key.
Protocol revision −2 — Support the current protocol revision.
Now: Speaks MCP 2025-11-25, 1 revision(s) behind 2026-07-28.

How many agent tools actually work · All statistics

Listed in

Directories this entry was found in.

smithery since 2026-06-10 ↗

How to connect

MCP endpoint (streamable-http)

https://server.smithery.ai/ranomics/platform/mcp

JSON-RPC initialize probe

curl -X POST https://server.smithery.ai/ranomics/platform/mcp \
  -H 'Content-Type: application/json' \
  -H 'Accept: application/json, text/event-stream' \
  -d '{"jsonrpc":"2.0","id":1,"method":"initialize","params":{}}'

Homepage

https://smithery.ai/servers/ranomics/platform

Listed at (smithery)

https://smithery.ai/servers/ranomics/platform